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Pixelgen - Broschure

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INTRODUCINGMOLECULARPIXELATION The next dimension in Spatial Proteomics for Single Cells, offering Novel insights into Human healthLET’S STAY IN TOUCHContact uswww.pixelgen.comhello@pixelgen.comPIONEERING SPATIAL PROTEOMICS OF SINGLE CELLS

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Life operates by the spatialorchestration of proteinsThe cell surface proteome isdynamic and spatial location ofproteins change with the state and activity of the cell, which in turn determines the cell’s activity in health and disease.Introducing Molecular Pixelation Molecular Pixelation (MPX)produces a 3D map of cell surface proteins using DNA-based, nanometer-sized molecular pixels. MPX enable new ways of understanding dynamic cell regulation through spatial reorganization, thereby opening up single cell studies for a new type of co-localization based protein biomarkers. These molecular insights in cell activity, will lead to new avenues of immunotherapy.”Our revolutionary Molecular Pixelation technology brings a new spatial dimension to the analysis of cell surface proteins, enabling the advancement of basic science and the acceleration of new therapeutics.”Simon FredrikssonCEOMissionUnderstanding biologyT-Cell Molecular Pixelation (MPX) DataMolecular Pixelation enables multiplex spatial analysis of surface proteins in terms of abundance, polarization and co-localization in thousands of single cells in parallel.• Deep Phenotyping• Single cell specificity without single cell isolation• No specialized equipment needed20Neg. ControlCD3-polarized100CD11A CD2 CD3 CD45

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Life operates by the spatialorchestration of proteinsThe cell surface proteome isdynamic and spatial location ofproteins change with the state and activity of the cell, which in turn determines the cell’s activity in health and disease.Introducing Molecular Pixelation Molecular Pixelation (MPX)produces a 3D map of cell surface proteins using DNA-based, nanometer-sized molecular pixels. MPX enable new ways of understanding dynamic cell regulation through spatial reorganization, thereby opening up single cell studies for a new type of co-localization based protein biomarkers. These molecular insights in cell activity, will lead to new avenues of immunotherapy.”Our revolutionary Molecular Pixelation technology brings a new spatial dimension to the analysis of cell surface proteins, enabling the advancement of basic science and the acceleration of new therapeutics.”Simon FredrikssonCEOMissionUnderstanding biologyT-Cell Molecular Pixelation (MPX) DataMolecular Pixelation enables multiplex spatial analysis of surface proteins in terms of abundance, polarization and co-localization in thousands of single cells in parallel.• Deep Phenotyping• Single cell specificity without single cell isolation• No specialized equipment needed20Neg. ControlCD3-polarized100CD11A CD2 CD3 CD45

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Life operates by the spatialorchestration of proteinsThe cell surface proteome isdynamic and spatial location ofproteins change with the state and activity of the cell, which in turn determines the cell’s activity in health and disease.Introducing Molecular Pixelation Molecular Pixelation (MPX)produces a 3D map of cell surface proteins using DNA-based, nanometer-sized molecular pixels. MPX enable new ways of understanding dynamic cell regulation through spatial reorganization, thereby opening up single cell studies for a new type of co-localization based protein biomarkers. These molecular insights in cell activity, will lead to new avenues of immunotherapy.”Our revolutionary Molecular Pixelation technology brings a new spatial dimension to the analysis of cell surface proteins, enabling the advancement of basic science and the acceleration of new therapeutics.”Simon FredrikssonCEOMissionUnderstanding biologyT-Cell Molecular Pixelation (MPX) DataMolecular Pixelation enables multiplex spatial analysis of surface proteins in terms of abundance, polarization and co-localization in thousands of single cells in parallel.• Deep Phenotyping• Single cell specificity without single cell isolation• No specialized equipment needed20Neg. ControlCD3-polarized100CD11A CD2 CD3 CD45

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INTRODUCINGMOLECULARPIXELATION The next dimension in Spatial Proteomics for Single Cells, offering Novel insights into Human healthLET’S STAY IN TOUCHContact uswww.pixelgen.comhello@pixelgen.comPIONEERING SPATIAL PROTEOMICS OF SINGLE CELLS

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INTRODUCINGMOLECULARPIXELATION The next dimension in Spatial Proteomics for Single Cells, offering Novel insights into Human healthLET’S STAY IN TOUCHContact uswww.pixelgen.comhello@pixelgen.comPIONEERING SPATIAL PROTEOMICS OF SINGLE CELLS